Kanab Creek is one of the many tributaries of the Grand Canyon. It begins in Kane County, Utah just south of the watershed to the Great Basin and flows south toward the Colorado River. It passes Kanab, Utah, crosses the border to Arizona near Fredonia, Arizona. It flows through the Kaibab Indian Reservation of the Paiute people and the 1984 designated Kanab Creek Wilderness, a Wilderness area, before its mouth in the Grand Canyon National Park.